課程資訊
課程名稱
生物統計原理
Principles of Biostatistics 
開課學期
111-1 
授課對象
公共衛生學院  全球衛生博士學位學程  
授課教師
吳亞克 
課號
MGH7048 
課程識別碼
853EM0480 
班次
 
學分
2.0 
全/半年
半年 
必/選修
必修 
上課時間
第1,2,3,4,5,6,7,8 週
星期一6,7(13:20~15:10)星期四6,7(13:20~15:10) 
上課地點
公衛601A公衛601A 
備註
本課程以英語授課。密集課程。全球衛生學程必修課,外系所學生欲選修者請先洽詢授課老師。
限本系所學生(含輔系、雙修生) 且 限公衛學院學生(含輔系、雙修生)
總人數上限:24人 
 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

The aim of this course is to introduce basic concepts of statistical analysis commonly used in public health and give some introduction to programming. The practical sessions will be given alongside lectures. The course consists of two parts: the "analytical method", which will provide an introduction of fundamental statistical methods used to extract hidden information in data, and "practical sessions" which will involve problem solving from the biostats and practice in programming on example of R, a freely available statistical software. Real-life examples from each aspect of global health research topics and latest literature are illustrated in the course. 

課程目標
At the end of the course, the students are expected to
1. Explain public health history, philosophy and values (D17-1)
2. Explain the role of quantitative and qualitative methods and sciences in describing and assessing a population’s health (D17-3)
3. Analyze epidemiological data as illustrative examples for R programming 
課程要求
The slides of each lecture and scientific papers for discussion will be available on the course website for students to download before each class. A preceding e-mail for calling sick before a lecture is essential. 
預期每週課後學習時數
 
Office Hours
備註: By appointment 
指定閱讀
To be assigned in each class. 
參考書目
1. [Pa] Pagano M, Gauvreau K, Mattie H. Principles of Biostatistics. CRC Press. 3rd edition. 2022
2. [DeGr] DeGroot MH, Schervish MJ. Probability and Statistics. Pearson 2011
3. [Ro] Rosner B. Fundamentals of Biostatistics. Brooks / Cole. 2015
4. Crawley MJ. The R book. Wiley 2012
5. The Epidemiologist R Handbook https://www.epirhandbook.com/en/index.html
 
評量方式
(僅供參考)
   
針對學生困難提供學生調整方式
 
上課形式
以錄音輔助, 以錄影輔助
作業繳交方式
學生與授課老師協議改以其他形式呈現
考試形式
其他
由師生雙方議定
課程進度
週次
日期
單元主題
Week 1
09/05, 09/08  Introduction. Descriptive statistics.
Random numbers. Mean and variance
[Pa] Ch. 1-2; [DeGr] Ch. 1.1–1.6 
Week 2
09/12, 09/15  Probabilities. Discrete and continuous distributions.
[Pa] Ch. 5, 8-9 
Week 3
09/19, 09/22  Statistical tests
[Ro] Ch. 7; [Pa] Ch. 10 
Week 4
09/26, 09/29  Statistical tests (cont.)
[Ro] Ch. 7–8; [Pa] Ch. 10

Chi2-test. Linear regression models
[Ro] Ch. 10–11; [DeGr] Ch. 10.1–10.3; [Pa] Ch. 15 
Week 5
10/03, 10/06  Linking statistical tests and linear regression models.
Explaining the written exam
[Ro] Ch. 11

Written exam 
Week 6
10/10, 10/13  National holiday (10/10)

Logistic regression
[Pa] Ch. 19 
Week 7
10/17, 10/20  Generalized linear models 
Week 8
10/24, 10/27  Survival analysis
[Pa] Ch. 20

More advanced topics on R and other programming languages for biostats. Explaining the home assignment